우석대학교 약학대학 한약학과 한약학사
우석대학교 대학원 한약학석사
우석대학교 대학원 한약학박사 (한방약리학 전공)
경력
2010.08 ~ 2011.02 : 헬스케어기술개발사업단 Postdoctoral Fellow
2011.03 ~ 2012.02 : Brody School of Medicine at ECU, USA Postdoctoral Fellow
2012.03 ~ 현재 : 우석대학교 약학대학 한약학과 교수
2012.03 ~ 현재 : 대한한약학회 운영이사
2013.03 ~ 현재 : 대한약학회 한약학분과회 총무간사
2013.07 ~ 현재 : 한국보건의료인국가시험원 한약사시험위원회 간사
2014.09 ~ 2016.06 : 우석대학교 기획처 기획평가팀 팀장
2014.10 ~ 2016.06 : 우석대학교 특성화센터 센터장
2014.11 ~ 현재 : 한국보건의료인국가시험원 한약관련과목 심사위원회 위원
- 연구분야
⦁ C. elegans 모델을 이용한 천연물의 약리 기전 연구
- 주요 연구실적
1. 논문
⦁ MPK‐1ERK is required for the full activity of resveratrol in extended lifespan and reproduction, Aging Cell (2019)
⦁ Synthesis and Evaluation of the Lifespan-Extension Properties of Oleracones D–F, Antioxidative Flavonoids from Portulaca oleracea L, Appl Sci (2019)
⦁ Non-Ionic Surfactants Antagonize Toxicity of Potential Phenolic Endocrine-Disrupting Chemicals, Including Triclosan in Caenorhabditis elegans, Mol Cell (2018)
⦁ Antiageing properties of Damaurone D in Caenorhabditis elegans, Journal of Pharmacy and Pharmacology (2018)
⦁ Subunits of the DNA polymerase alpha-primase complex promote Notch-mediated proliferation with discrete and shared functions in C. elegans germline, FEBS Journal (2018)
⦁ Measurement of Intracellular ROS in Caenorhabditis elegans Using 2’,7’-Dichlorodihydrofluorescein Diacetate, Bioprotocol (2018)
⦁ Triclosan Disrupts SKN-1Nrf2-Mediated Oxidative Stress Response in C. elegans and Human Mesenchymal Stem Cells, Scientific Reports (2017)
⦁ Sorbus alnifolia protects dopaminergic neurodegeneration in Caenorhabditis elegans, Pharmaceutical Biology (2016)
⦁ Anti-aging properties of Ribes fasciculatum in Caenorhabditis elegans, Chin J Nat Med, (2016)
⦁ A systematic mRNA control mechanism for germline stem cell homeostasis and cell fate specification, BMB Rep, (2016)
⦁ Lifespan Extending and Stress Resistant Properties of Vitexin from Vigna angularis in Caenorhabditis elegans, Biomol Ther, (2015)
⦁ Catalpol Modulates Lifespan via DAF-16/FOXO and SKN-1/Nrf2 Activation in Caenorhabditis elegans, Evid Based Complement Alternat Med, (2015)
⦁ Genistein from Vigna angularis Extends Lifespan in Caenorhabditis elegans, Biomol Ther, (2015)
⦁ Transgene-mediated co-suppression of DNA Topoisomerase-1 gene in Caenorhabditis elegans, International Journal of Biochemistry and Molecular biology, (2014)
⦁ 4-Hydroxybenzoic acid-mediated lifespan extension in Caenorhabditis elegans, Journal of Functional Foods, (2014)
⦁ Protocatechuic acid extends lifespan and increases stress resistance in Caenorhabditis elegans, Archives of Pharmacal Research, (2014)
⦁ The Longevity Properties of 1,2,3,4,6-Penta-O-Galloyl-β-D- Glucose from Curcuma longa in Caenorhabditis elegans, Biomolecules & Therapeutics, (2013)
⦁ Anti-inflammatory and anti-nociceptive properties of Prunus padus, Journal of Ethnopharmacology, (2012)
⦁ The Ras-ERK MAPK regulatory network controls dedifferentiation in Caenorhabditis elegans germline, Biochimica et Biophysica Acta-Molecular Cell Research, (2012)
⦁ Differential subcellular localization of DNA topoisomerase-1 isoforms and their roles during Caenorhabditis elegans development, Gene Expression Patterns, (2012)
⦁ Post-transcriptional regulation of the Ras-ERK/MAPK signaling pathway, Journal of Cellular Physiology, (2012)
⦁ Anti-metastatic Properties of the Leaves of Eriobotrya japonica, Archives of Pharmacal Research, (2011)
⦁ Anti-inflammatory and antinociceptive properties of the leaves of Eriobotrya japonica, Journal of Ethnopharmacology, (2011)
⦁ Antinociceptive and hypnotic properties of Celastrus orbiculatus, Journal of Ethnopharmacology, (2011)
2. 저서
⦁ 한방약리학(공저), 신일북스 (2015)
⦁ 기능성식품학(공저), 신일서적 (2017)
3. 특허
⦁ 노박덩굴 추출물을 포함하는 통증억제용 조성물 (2013)
⦁ 4-하이드록시벤조산을 유효성분으로 함유하는 수명연장 및 노화방지용 조성물 (2014)