교수진소개

리뷰 네비게이션

Department of Oriental Pharmacy
실력과 전문성을 겸비한 한약사 양성의 요람

본문내용

교수진소개

목록
교수사진
  • 성     명 : 안지혜 (Ji-Hye Ahn)
  • 소     속 : 약학대학 한약학과 (Department of Oriental Pharmacy, College of Pharmacy)
  • 구     분 : 전임교원 (Assistant Professor)
  • 전화번호 : +82-63-290-1580
  • 이  메 일 : jihyeahn20@woosuk.ac.kr
  • 홈페이지 : https://hanyak.woosuk.ac.kr/2015/img/Ahn.pdf
  • 학력
    2007.03 ～ 2011.02 : 경희대학교 약학대학 한약학과 한약학사
    2011.03 ～ 2012.08 : 경희대학교 대학원 약학석사
    2012.09 ～ 2017.02 : 경희대학교 대학원 한약학박사
  • 경력
    [Education]

    ⦁ 2012–2017 : Ph.D. Oriental Pharmacy
    Thesis : Ovarian Cancer Metastasis : the roles of nc886, mutant p53, and prostacyclin
    Department of Life and Nanopharmaceutical Sciences and Department of Oriental
    Pharmaceutical Science
    Kyung Hee University, Seoul, South Korea
    ⦁ 2011-2012 : M.S. Pharmacy
    Thesis : Prostacyclin suppresses the migration and invasion via down-regulation of
    matrix metalloprotease-2 (MMP-2) in ovarian cancer cells Department of Life and
    Nanopharmaceutical Sciences and Department of Oriental
    Pharmaceutical Science
    Kyung Hee University, Seoul, South Korea
    ⦁ 2007-2011 : B.S. Oriental Pharmacy
    Department of Oriental Pharmaceutical Science
    Kyung Hee University, Seoul, South Korea

    [Honors and Awards]

    ⦁ 2017 : Outstanding Thesis Award
    ⦁ 2014 : Outstanding Graduate Student Award

    [Professional and Academic Experience]

    ⦁ 2020.03-present : Assistant Professor, Department of Korean Pharmacy, Woosuk University
    ⦁ 2018.09-2020.02 : Post-doctoral Researcher, Department of Biochemistry and Molecular Genetics,
    University of Virginia School of Medicine
    ⦁ 2017.10-2018.08 : Research Professor, College of Pharmacy, Kyung Hee University
    ⦁ 2017.03-2017.09 : Adjunct faculty, Medical Research Center, Kyung Hee University
    ⦁ 2016.10-2017.02 : Graduate Research Assistant, College of Pharmacy, Kyung Hee University
    ⦁ 2016.03-2016.06 : Graduate Teaching Assistant, College of Pharmacy, Kyung Hee University
    ⦁ 2015.09-2016.02 : Visiting Student Research Assistant, Department of Biochemistry and Molecular
    Biology, University of Texas Medical Branch
    ⦁ 2015.03-2015.06 : Graduate Teaching Assistant, College of Pharmacy, Kyung Hee University
    ⦁ 2011.09-2012.02 : Graduate Research Assistant, College of Pharmacy, Kyung Hee University

    [Publications] (* First author/Corresponding author)

    ⦁ Kwon KM, Kim EH, Sim KH, Lee YJ, Kang EJ, Han KH, Jin JS, Kim DK, Ahn JH*, Hwang IH. Phenylacetic acid, an anti-vaginitis metabolite produced by the vaginal symbiotic bacterium Chryseobacterium gleum. Sci Rep. 2024 May 28;14(1):12226.
    ⦁ Yang YI, Wang YY, Ahn JH, Kim BH, Choi JH. CCL2 overexpression is associated with paclitaxel resistance in ovarian cancer cells via autocrine signaling and macrophage recruitment. Biomed Pharmacother. 2022
    Sep;153:113474.
    ⦁ Choi HY, Ahn JH, Kwon H, Yim JH, Lee D, Choi JH. Citromycin Isolated from the Antarctic Marine-Derived
    Fungi, Sporothrix sp., Inhibits Ovarian Cancer Cell Invasion via Suppression of ERK Signaling. Mar Drugs. 2022 Apr 20;20(5):275.
    ⦁ Ahn JH*, Choi JM, Kang ES, Yoo JH, Cho YJ, Jang DS, Choi JH. The Anti-Endometriotic Effect of Cyperi Rhizoma Extract, Inhibiting Cell Adhesion and the Expression of Pain-Related Factors through Akt and NF-kB Pathways. 2022 Feb 23;58(3):335.
    ⦁ Choi JG, Jeong M, Joo BR, Ahn JH, Woo JH, Kim DH, Oh MS, Choi JH. Reduced Levels of Intestinal
    Neuropeptides and Neurotrophins in Neurotoxin-Induced Parkinson Disease Mouse Models. J Neuropathol
    Exp Neurol. 2020 Oct 1:nlaa113.
    ⦁ Ahn JH*, Jang DS, Choi JH. Lancemaside A Isolated from the Root of Codonopsis lanceolata Inhibits Ovarian Cancer Cell Invasion via the Reactive Oxygen Species (ROS)-Mediated p38 Pathway. Am J Chin Med.
    2020;48(4):1021-1034.
    ⦁ Chatrath A, Przanowska R, Kiran S, Su Z, Saha S, Wilson B, Tsunematsu T, Ahn JH, Lee KY, Paulsen T, Sobierajska E, Kiran M, Tang X, Li T, Kumar P, Ratan A, Dutta A. The pan-cancer landscape of prognostic germline variants in 10,582 patients. Genome Med. 2020 Feb 17;12(1):15.
    ⦁ Woo JH, Ahn JH, Jang DS, Choi JH. Effect of Dehydrocostus Lactone Isolated from the Roots of Aucklandia
    lappa on the Apoptosis of Endometriotic Cells and the Alternative Activation of Endometriosis-Associated Macrophages. Am J Chin Med. 2019;47(6):1289-1305.
    ⦁ Ahn JH*, Woo JH, Rho JR, Choi JH. Anticancer Activity of Gukulenin A Isolated from the Marine Sponge
    Phorbas gukhulensis In Vitro and In Vivo. Mar Drugs. 2019 Feb 21;17(2):126.
    ⦁ Du YE, Lee JS, Kim HM, Ahn JH, Jung IH, Ryu JH, Choi JH, Jang DS. Chemical constituents of the roots of
    Codonopsis lanceolata. Arch Pharm Res. 2018 Nov;41(11):1082-1091.
    ⦁ Ahn JH*, Lee HS, Lee JS, Lee YS, Park JL, Kim SY, Hwang JA, Kunkeaw N, Jung SY, Kim TJ, Lee KS, Jeon SH, Lee IH, Johnson BH, Choi JH, Lee YS. nc886 is induced by TGF-β and suppresses the microRNA pathway in ovarian cancer. Nat Commun. 2018 Mar 21;9(1):1166.
    ⦁ Lee K, Ahn JH, Lee KT, Jang DS, Choi JH. Deoxyschizandrin, Isolated from Schisandra Berries, Induces Cell Cycle Arrest in Ovarian Cancer Cells and Inhibits the Protumoural Activation of Tumour-Associated Macrophages. Nutrients. 2018 Jan 15;10(1).
    ⦁ Ahn JH*, Lee KT, Choi YS, Choi JH. Iloprost, a prostacyclin analog, inhibits the invasion of ovarian cancer cells by downregulating matrix metallopeptidase-2 (MMP-2) through the IP-dependent pathway. Prostaglandins Other Lipid Mediat. 2018 Jan;134:47-56.
    ⦁ Jeong M, Kim HM, Ahn JH, Lee KT, Jang DS, Choi JH. 9-Hydroxycanthin-6-one isolated from stem bark of Ailanthus altissima induces ovarian cancer cell apoptosis and inhibits the activation of tumor-associated macrophages. Chem Biol Interact. 2018 Jan 25;280:99-108.
    ⦁ Park JL, Lee YS, Song MJ, Hong SH, Ahn JH, Seo EH, Shin SP, Lee SJ, Johnson BH, Stampfer MR, Kim HP, Kim SY, Lee YS. Epigenetic regulation of RNA polymerase III transcription in early breast tumorigenesis. Oncogene. 2017 Dec 7;36(49):6793-6804.
    ⦁ Woo JH, Yang YI, Ahn JH, Choi YS, Choi JH. IL6 secretion from alternatively activated macrophages promotes the migration of endometriotic epithelial cells. Biol Reprod. 2017 Nov 1;97(5):660-670.
    ⦁ Woo JH, Ahn JH, Jang DS, Lee KT, Choi JH. Effect of Kumatakenin Isolated From Cloves on the Apoptosis of Cancer Cells and the Alternative Activation of Tumor-Associated Macrophages. J Agric Food Chem. 2017 Sep 13;65(36):7893-7899
    ⦁ Ahn JH*, Kim TJ, Lee JH, Choi JH. Mutant p53 stimulates cell invasion through an interaction with Rad21 in human ovarian cancer cells. Sci Rep. 2017 Aug 22;7(1):9076.
    ⦁ Lee JG, Ahn JH*, Jin Kim T, Ho Lee J, Choi JH. Mutant p53 promotes ovarian cancer cell adhesion to mesothelial cells via integrin β4 and Akt signals. Sci Rep. 2015 Jul 30;5:12642.
    ⦁ Ahn JH*, Choi YS, Choi JH. Leptin promotes human endometriotic cell migration and invasion by up-regulating MMP-2 through the JAK2/STAT3 signaling pathway. Mol Hum Reprod. 2015 Oct;21(10):792-802.
    ⦁ Lee JS, Ahn JH, Cho YJ, Kim HY, Yang YI, Lee KT, Jang DS, Choi JH. α-Terthienylmethanol, isolated from Eclipta prostrata, induces apoptosis by generating reactive oxygen species via NADPH oxidase in human endometrial cancer cells. J Ethnopharmacol. 2015 Jul 1;169:426-34.
    ⦁ Ahn JH*, Lee TW, Kim KH, Byun H, Ryu B, Lee KT, Jang DS, Choi JH. 6-Acetoxy Cyperene, a Patchoulane-type Sesquiterpene Isolated from Cyperus rotundus Rhizomes Induces Caspase-dependent Apoptosis in Human
    Ovarian Cancer Cells. Phytother Res. 2015 Jun 10.
    ⦁ Yang YI, Ahn JH, Choi YS, Choi JH. Brown algae phlorotannins enhance the tumoricidal effect of cisplatin and ameliorate cisplatin nephrotoxicity. Gynecol Oncol. 2015 Feb;136(2):355-64.
    ⦁ Ahn JH*, Yang YI, Lee KT, Choi JH. Dieckol, isolated from the edible brown algae Ecklonia cava, induces
    apoptosis of ovarian cancer cells and inhibits tumor xenograft growth. J Cancer Res Clin Oncol. 2015
    Feb;141(2):255-68.
    ⦁ Yang YI, Ahn JH, Lee KT, Shih IeM, Choi JH. RSF1 is a positive regulator of NF-κB-induced gene expression required for ovarian cancer chemoresistance. Cancer Res. 2014 Apr 15;74(8):2258-69.
    ⦁ Lee JG, Kim JH, Ahn JH, Lee KT, Baek NI, Choi JH. Jaceosidin, isolated from dietary mugwort (Artemisia
    princeps), induces G2/M cell cycle arrest by inactivating cdc25C-cdc2 via ATM-Chk1/2 activation. Food Chem Toxicol. 2013 May;55:214-21.
    ⦁ Kim JH, Jung SH, Yang YI, Ahn JH, Cho JG, Lee KT, Baek NI, Choi JH. Artemisia leaf extract induces apoptosis in human endometriotic cells through regulation of the p38 and NFκB pathways. J Ethnopharmacol. 2013 Feb 13;145(3):767-75.
    ⦁ Kim JH, Yang YI, Ahn JH, Lee JG, Lee KT, Choi JH. Deer (Cervus elaphus) antler extract suppresses adhesion and migration of endometriotic cells and regulates MMP-2 and MMP-9 expression. J Ethnopharmacol. 2012 Mar 27;140(2):391-7.
    ⦁ Cho JH, Lee JG, Yang YI, Kim JH, Ahn JH, Baek NI, Lee KT, Choi JH. Eupatilin, a dietary flavonoid, induces G2/M cell cycle arrest in human endometrial cancer cells. Food Chem Toxicol. 2011 Aug;49(8):1737-44.

    [Research accomplishments]

    ⦁ 2020.06-2025.05 : The role of lncRNA in chemoresistance of ovarian cancer and tumor
    microenvironment and its mechanism of action
    ⦁ 2018.09-2019.08 : The role of a mutant p53-induced long non-coding RNA in promoting ovarian
    cancer

    [Conference contributions]

    ⦁ Alterations of intestinal neurotrophins in neurotoxin- induced Parkinson’s disease mouse model
    2020 Korean Society for Biochemistry and Molecular Biology, International Conference. 2020.09
    ⦁ The roles of nc886, a novel type of non-coding RNA, in ovarian cancer
    2017 Korean Society for Biochemistry and Molecular Biology, International Conference. 2017.05
    ⦁ The roles of nc886, a novel type of non-coding RNA, in ovarian cancer
    2015 Korean-American Biomedical Scientists Symposium. 2015.11
    ⦁ Leptin increase the migration and invasion abilities of endometriotic cells via the upregulation of
    MMP2
    2015 Annual Meeting of the Korean Society of Applied Pharmacology. 2015.10.
    ⦁ 6-acetoxy cyperene, isolated from the rhizomes of cyperus rotundus, induces apoptosis of human
    ovarian cancer cells in a caspase-dependent manner
    2015 Annual Meeting of the Korean Society of Applied Pharmacology. 2015.10.
    ⦁ Mutant p53 enhances the metastatic potential of ovarian cancer cells
    2014 Fall International Convention of The Pharmaceutical Society of Korea. 2014.10.
    ⦁ Patcoulan-4-ene-6-ol acetate isolated from cyperus rotundus induces apoptosis in human ovarian
    cancer cells
    2013 Spring International Convention of The Pharmaceutical Society of Korea. 2013.04.
    ⦁ Dieckol, Isolated From Marine Brown Algae Ecklonia cava, Induces ROS-mediated apoptosis in
    human ovarian cancer cells Via the Multiple Signaling Pathways
    24th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics. 2012.11.
    ⦁ Prostacyclin suppresses the migration and invasion via down-regulation of matrix
    metalloproteinase-2 in ovarian cancer cells
    2012 KSBMB annual meeting. 2012.5.
    ⦁ Expression of prostacyclin receptor and potential effects of prostacyclin on the ell migration and
    expression of matrix metalloproteinase in ovarian cancer cells
    14th world Congress on ob,gyn & infertility. 2011.11.
    ⦁ Eupatilin and jaceosidin isolated from artemisia princeps induce G2/M cell cycle arrest in human
    endometrial cancer cells
    16th international charles heidelberger symposium on cancer research. 2010.09.
목록

리뷰 네비게이션